Suit 47365 Batwing amp; Knit Sleeves Size Hawaii n 34 Bust Wash Orange Tunic Wear Hawaiian Shirt Pant Pants Made 6 in Floral qYt18

Preeclampsia was once called “the disease of theories,” but research efforts this past decade have produced exciting breakthroughs that may bring us closer to causality, improve diagnosis and even prediction, and lead to prevention and/or specific treatments. Some speculation remains over different theories including: changes in biology of the placenta, the systemic inflammatory response, a variety of hormones and other proteins that are in the mother’s circulation, changes in immune factors, improper cardiovascular adaptations to the pregnant state, underlying maternal risks for cardiovascular disease, associations with insulin resistance and diabetes, and deficiencies in essential nutrients, minerals, and vitamins. 

The most plausible theories focus on the placenta and describe the disorder in two stages. In the first, the initiating cause results in the placenta producing factors (e.g., specific proteins, placental “debris”) that enter the maternal circulation and are believed responsible for producing the next stage. This is the second stage, which results in the overt maternal “disease” (high blood pressure, kidney, liver and coagulation abnormalities).  The overt disease depends not only on the action of the circulating factors from the placenta, but also the health of the mother, including diseases that may affect the vasculature (such as preexisting cardiovascular, renal, metabolic, and genetic factors; and obesity). A quick chart of potential causes can be found in our FAQsMan Rave Futuristic Clothing Hippie Clothes clothing Windbreaker Sacred Jacket Festival Clothes Burning Geometry Music Clothing Ravewear Men Fwn1qS.

Batwing amp; Tunic Floral Hawaii n 34 Pants 47365 6 Size Suit in Orange Pant Sleeves Hawaiian Wash Made Knit Shirt Bust Wear
A promising area of recent research involves the role of proteins produced by the placenta that inhibit angiogenesis (the production of new blood vessels).  Two of these “antiangiogenic factors” (soluble Fms-like tyrosine kinase-1, and soluble endoglin) have been shown to produce a preeclampsia like disease in rodents. Their concentrations rise in the mother’s circulation weeks to months before the disease manifests.  Placentas of women destined to develop preeclampsia overproduce these proteins that then enter the mother’s circulation.  Neutralizing their actions is now being investigated in animal models, and in some studies has reversed the disease in rodents. .  Excitement regarding these interventions is tempered by a limited understanding of the functional role of antiangiogenic substances in normal pregnancy.

If the ability of these antiangiogenic proteins to cause preeclampsia is confirmed by research in humans, why the placenta overproduces them remains unknown. Hence, many of the other areas of investigation mentioned above may be important.  Preeclampsia may have multiple causes, and other leads are being investigated, including prostaglandins, digoxin-like molecules, immunological mechanisms, autoantibodies that trigger receptors that lead to vessel constriction (agonistic autoantibodies to the angiotensin 1 receptor), oxidative stress, mitochondrial pathology, the impact of hypertension and prehypertension on endovascular health, and genes sensitive to low oxygen environments. 

Basic research into causes of preeclampsia, lacking for decades, is being revitalized, albeit more slowly than needed. While we are moving closer to historically elusive answers, the true cause of preeclampsia remains unknown. Successful ongoing  research needs far more support and funding.

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amp; Shirt in Wash n Orange Made Knit Wear 47365 Suit Size Floral Hawaii Bust Batwing 34 Sleeves Tunic Pants 6 Hawaiian Pant
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Suit 47365 Batwing amp; Knit Sleeves Size Hawaii n 34 Bust Wash Orange Tunic Wear Hawaiian Shirt Pant Pants Made 6 in Floral qYt18 Suit 47365 Batwing amp; Knit Sleeves Size Hawaii n 34 Bust Wash Orange Tunic Wear Hawaiian Shirt Pant Pants Made 6 in Floral qYt18 Suit 47365 Batwing amp; Knit Sleeves Size Hawaii n 34 Bust Wash Orange Tunic Wear Hawaiian Shirt Pant Pants Made 6 in Floral qYt18 Suit 47365 Batwing amp; Knit Sleeves Size Hawaii n 34 Bust Wash Orange Tunic Wear Hawaiian Shirt Pant Pants Made 6 in Floral qYt18 Suit 47365 Batwing amp; Knit Sleeves Size Hawaii n 34 Bust Wash Orange Tunic Wear Hawaiian Shirt Pant Pants Made 6 in Floral qYt18
Love this breezy pant outfit from the late 60s! It's a two-piece casual pantsuit in an elegant wildflowers print, with a batwing sleeved tunic top and chic belled-leg pants. The top has a slash neckline that buttons at either shoulder and a curved hem.







Ladies' Size



6 to 7







Measurements



Bust 34, Waist 24 to 31, Hip 36.5; Shirt Neck to Hem 26, Pant Inseam 30.25, Outseam 41 Inches







Era



1960s







Label



' MADE IN HAWAII BY / dael's Casuals ' and vintage size 10 at back neck, similar label in pant







Materials



Sherbet orange silky-smooth polyester knit, lightweight and opaque, printed with red-orange sketched style grasses and white wildflower silhouettes







Closure



None needed on tunic shirt (shoulder buttons & loops are functional), elasticized waist on pant







Condition



Excellent







Condition Detail



Looks unworn or perhaps barely worn, essentially mint with no flaws







Washing Instructions



Warm gentle machine wash, hang to dry, steam if needed







Please note: All measurements (bust - waist - hip) are the maximum body measurements that will fit the item. These measurements already have ease subtracted and they are not actual fabric widths. To get actual fabric widths add two inches at the bust - one inch at the waist and two inches at the hip.







Size listed is a modern size. Any available vintage size is noted in the Label description. Please remember vintage sizes and modern sizes can vary a great deal.







Additional photos are often available - please message us and we'll be glad to reply.



Please let us know if you have any questions!







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